Stigma sterol is a natural phytosterol—plant-derived sterol—characterized
by its tetracyclic triterpene structure (C₁₉H₄₈O) and crystalline white form. Naturally
found in soybean, rapeseed, nuts, seeds, and medicinal herbs, it plays a vital role in plant
membrane stability and stress resistance
Breakthrough Plant-Based Sterol Extraction
Our cutting-edge process isolates premium-grade stigmasterol from botanical sources such
as soy, corn, and traditional Indian medicinal plants like Roscoea purpurea. We employ
advanced spectroscopic (NMR, LCMS) and chromatographic techniques—ensuring a chemically
pure, crystalline product with superior stability (shelf‐life of 2+ years at –20 °C)
Multi-faceted Applications
Pharmaceutical & Nutraceutical
- Cholesterol-lowering agent—reduces LDL by ~6–10% at 2 g/day via inhibition of
intestinal absorption
- Key precursor for synthesizing progesterone, corticosteroids, and vitamin D₃—used
industrially since the 1950s
Therapeutic Research
- Anti-inflammatory & immunomodulatory—modulates TNF‑α, IL‑6, NF‑κB & p38‑MAPK
pathways
- Antioxidant & neuroprotective—neutralizes ROS, inhibits lipid peroxidation, and
supports acetylcholinesterase control
- Anticancer efficacy—induces apoptosis via Akt/mTOR & VEGFR‑2 pathway inhibition in
tumor models
Functional Foods & Cosmetic Formulations
- Used as additive E499 in fortified spreads & health foods to support cardiovascular
wellness
- Incorporated in anti-diabetic nanoemulsion foods—α‑amylase inhibition & glycemic
control proven in animal studies
- Advances cosmeceuticals with anti-inflammatory and antioxidant benefits for skin
repair and anti-aging
Bioprocess & Drug Delivery
- Acts as a cholesterol analogue in lipid nanoparticle (LNP) systems—improving
mRNA-LNP stability and transfection efficiency
Contact us to discuss how IBHA's stigma sterol can elevate your R&D, formulation, and product pipelines.
